January 10, 2012
How does emphysema and congestive heart failure affect acid-base imbalance?

One Response to “How does emphysema and congestive heart failure affect acid-base imbalance?”
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January 10th, 2012 at 12:42 pm
Patients with advanced heart failure commonly develop simple or mixed acid-base disturbances. The altered acid-base homeostasis can occur as a consequence of the heart failure itself, the therapeutic interventions, or associated conditions. When heart transplantation is undertaken, in patients before heart transplantation there is a mixed acid-base imbalance that includes respiratory alkalosis and metabolic alkalosis. After transplantation the recovery of the abnormal circulatory status erases the initial respiratory alkalosis but metabolic alkalosis usually persists and accounts for a further rise in plasma bicarbonate.
I add a link with technical details covering this subject, and distribution of other body fluids
http://circ.ahajournals.org/
cgi/reprint/4/5/697.pdf
Hope this helps
matador 89